Version 5.4
Homo sapiens Protein: DEPTOR
Summary
InnateDB Protein IDBP-485141.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DEPTOR
Protein Name DEP domain containing MTOR-interacting protein
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000430457
InnateDB Gene IDBG-34051 (DEPTOR)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006469 negative regulation of protein kinase activity
GO:0032007 negative regulation of TOR signaling
GO:0035556 intracellular signal transduction
GO:0045792 negative regulation of cell size
GO:2001236 regulation of extrinsic apoptotic signaling pathway
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID
InterPro IPR000591 DEP domain
IPR001478 PDZ domain
PFAM PF00610
PF00595
PF13180
PRINTS
PIRSF
SMART SM00049
SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8TB45
PhosphoSite PhosphoSite-Q8TB45
TrEMBL
UniProt Splice Variant
Entrez Gene 64798
UniGene Hs.112981
RefSeq NP_001269941
HUGO HGNC:22953
OMIM 612974
CCDS CCDS64960
HPRD 13137
IMGT
EMBL AC091563 AK022490 AK023916 AK297822 AK315175 AL136678 AP005717 BC012040 BC024746 CH471060
GenPept AAH12040 AAH24746 BAB14054 BAB14723 BAG37616 BAG60159 CAB66613 EAW91997

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca