Version 5.4
Homo sapiens Protein: PKD2
Summary
InnateDB Protein IDBP-485229.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PKD2
Protein Name polycystic kidney disease 2 (autosomal dominant)
Synonyms APKD2; Pc-2; PC2; PKD4; TRPP2;
Species Homo sapiens
Ensembl Protein ENSP00000427131
InnateDB Gene IDBG-29443 (PKD2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 26 [view]
Protein-Protein 25 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005509 calcium ion binding
Biological Process
GO:0006811 ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR002048 EF-hand domain
IPR003915 Polycystic kidney disease type 2 protein
IPR005821 Ion transport domain
IPR013122 Polycystin cation channel, PKD1/PKD2
PFAM PF00036
PF13202
PF13405
PF00520
PF08016
PRINTS PR01433
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9UEU6
UniProt Splice Variant
Entrez Gene 5311
UniGene Hs.604393
RefSeq
HUGO HGNC:9009
OMIM 173910
CCDS
HPRD 01437
IMGT
EMBL AC084732 AF054992 AK293461 AK294173 AK294589
GenPept AAC09351 BAG56956 BAG57494 BAH11820

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca