Version 5.4
Homo sapiens Protein: MRPS22
Summary
InnateDB Protein IDBP-485331.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRPS22
Protein Name mitochondrial ribosomal protein S22
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000418008
InnateDB Gene IDBG-58802 (MRPS22)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Mitochondrion.
Disease Associations Combined oxidative phosphorylation deficiency 5 (COXPD5) [MIM:611719]: A mitochondrial disease resulting in severe metabolic acidosis, edema, hypertrophic cardiomyopathy, tubulopathy, and hypotonia. {ECO:0000269PubMed:17873122}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
Experimentally validated
Total 41 [view]
Protein-Protein 41 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005739 mitochondrion
GO:0005761 mitochondrial ribosome
GO:0005763 mitochondrial small ribosomal subunit
Protein Structure and Domains
PDB ID
InterPro IPR019374 Ribosomal protein S22, mitochondrial
PFAM PF10245
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P82650
PhosphoSite PhosphoSite-P82650
TrEMBL Q96Q16
UniProt Splice Variant
Entrez Gene 56945
UniGene Hs.75724
RefSeq XP_005247697
HUGO HGNC:14508
OMIM 605810
CCDS CCDS3107
HPRD 10430
IMGT
EMBL AB061314 AF226045 AF321613 BC009296
GenPept AAF86945 AAH09296 AAK01406 BAB54962

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca