Version 5.4
Homo sapiens Protein: SLCO6A1
Summary
InnateDB Protein IDBP-485376.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLCO6A1
Protein Name solute carrier organic anion transporter family, member 6A1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000421339
InnateDB Gene IDBG-35454 (SLCO6A1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Strongly expressed in testis. Weakly expressed in spleen, brain, fetal brain and placenta. Detected in lung tumors. {ECO:0000269PubMed:12677006, ECO:0000269PubMed:15546177}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002350 Kazal domain
IPR004156 Organic anion transporter polypeptide OATP
IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
PFAM PF00050
PF07648
PF03137
PF07690
PRINTS
PIRSF
SMART SM00280
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86UG4
PhosphoSite PhosphoSite-Q86UG4
TrEMBL H0Y8R6
UniProt Splice Variant
Entrez Gene 133482
UniGene Hs.388874
RefSeq NP_775759
HUGO HGNC:23613
OMIM 613365
CCDS CCDS34206
HPRD 15400
IMGT
EMBL AC094108 AC113417 AF505657 AK131445 AY273897 BC034976 CH471086
GenPept AAH34976 AAP30851 AAP33048 BAD18590 EAW49095 EAW49096 EAW49097

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca