InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ABCA10

Summary

InnateDB Protein

IDBP-485562.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABCA10

Protein Name

ATP-binding cassette, sub-family A (ABC1), member 10

Synonyms

EST698739;

Species

Homo sapiens

Ensembl Protein

ENSP00000429853

InnateDB Gene

IDBG-66346 (ABCA10)

Protein Structure

UniProt Annotation

Function

Probable transporter which may play a role in macrophage lipid homeostasis.

Subcellular Localization

Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Widely expressed. Highly expressed in skeletal muscle, heart, brain and gastrointestinal tract. {ECO:0000269PubMed:12821155, ECO:0000269Ref.1}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005524	ATP binding
GO:0016887	ATPase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0006810	transport

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8WWZ4

PhosphoSite

PhosphoSite-Q8WWZ4

TrEMBL

UniProt Splice Variant

Entrez Gene

10349

UniGene

Hs.739016

RefSeq

HUGO

HGNC:30

OMIM

612508

CCDS

HPRD

12400

IMGT

EMBL

AC005495 AL832004 AY028900 AY247065 AY247069 AY247070 AY247071 AY247072 AY247073 AY247074 AY247075 AY247076 AY247077 AY247078 AY247079 AY247080 AY247081 AY247082 AY247083 AY247084 AY247085 AY247086 AY247087 AY247088 AY247089 AY247090 AY247091 AY247092 AY247093 AY247094 AY247095 AY247096 AY247097 AY247098 AY247099 AY247100 AY247101 AY247102 AY247103 AY247104 AY247105 BC031026 BC051320

GenPept

AAH31026 AAH51320 AAK30025 AAO72160 AAO72161 CAD89903