InnateDB Protein
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IDBP-48779.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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KRR1
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Protein Name
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KRR1, small subunit (SSU) processome component, homolog (yeast)
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Synonyms
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HRB2; RIP-1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000229214
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InnateDB Gene
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IDBG-48777 (KRR1)
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Protein Structure
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Function |
Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm. Nucleus, nucleolus. Note=Translocates from cytoplasm to nucleus after exposure to HIV- 1 virus or HIV-1 protein VPR or induction by hydrocortisone and dexamethasone in the absence of HIV-1 protein VPR.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
27
[view]
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Protein-Protein |
26
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR004087
K Homology domain
IPR004088
K Homology domain, type 1
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PFAM |
PF00013
PF13014
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PRINTS |
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PIRSF |
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SMART |
SM00322
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TIGRFAMs |
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Modification |
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SwissProt |
Q13601
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PhosphoSite |
PhosphoSite-Q13601
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
11103
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UniGene |
Hs.665628
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RefSeq |
NP_008974
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HUGO |
HGNC:5176
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OMIM |
612817
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CCDS |
CCDS9012
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HPRD |
11027
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IMGT |
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EMBL |
AC022507
AC121761
AK313687
BC005225
BC016778
BC026107
BC033887
EF010919
U55766
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GenPept |
AAB00557
AAH05225
AAH16778
AAH26107
AAH33887
ABJ97679
BAG36436
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