Version 5.4
Homo sapiens Protein: KRTAP4-4
Summary
InnateDB Protein IDBP-48822.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRTAP4-4
Protein Name keratin associated protein 4-4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000375076
InnateDB Gene IDBG-48818 (KRTAP4-4)
Protein Structure
UniProt Annotation
Function In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in the hair follicles. {ECO:0000269PubMed:15955084}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0045095 keratin filament
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BYR3
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 84616
UniGene Hs.307022
RefSeq NP_115913
HUGO HGNC:16928
OMIM
CCDS CCDS11383
HPRD 13945
IMGT
EMBL AC100808 AJ296168 AJ406936
GenPept CAC27563 CAC27575

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca