Version 5.4
Homo sapiens Protein: KRT31
Summary
InnateDB Protein IDBP-49079.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRT31
Protein Name keratin 31
Synonyms Ha-1; HA1; hHa1; KRTHA1;
Species Homo sapiens
Ensembl Protein ENSP00000251645
InnateDB Gene IDBG-49077 (KRT31)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Present in scalp but not in hairless skin. Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla. {ECO:0000269PubMed:9457912, ECO:0000269PubMed:9756910}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
Experimentally validated
Total 26 [view]
Protein-Protein 26 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005200 structural constituent of cytoskeleton
Biological Process
GO:0008544 epidermis development
Cellular Component
GO:0005615 extracellular space
GO:0005882 intermediate filament
Protein Structure and Domains
PDB ID
InterPro IPR001664 Intermediate filament protein
IPR002957 Keratin, type I
IPR009053 Prefoldin
PFAM PF00038
PRINTS PR01248
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q15323
PhosphoSite PhosphoSite-Q15323
TrEMBL Q16275
UniProt Splice Variant
Entrez Gene 3881
UniGene Hs.41696
RefSeq NP_002268
HUGO HGNC:6448
OMIM 601077
CCDS CCDS11391
HPRD 03047
IMGT
EMBL BC114468 CH471152 S75797 X86570 Y16787
GenPept AAB32812 AAI14469 CAA60378 CAA76383 EAW60730

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca