Version 5.4
Homo sapiens Protein: BRMS1L
Summary
InnateDB Protein IDBP-4908.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BRMS1L
Protein Name breast cancer metastasis-suppressor 1-like
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000216807
InnateDB Gene IDBG-4906 (BRMS1L)
Protein Structure
UniProt Annotation
Function Involved in the histone deacetylase (HDAC1)-dependent transcriptional repression activity. When overexpressed in lung cancer cell line that lacks p53/TP53 expression, inhibits cell growth. {ECO:0000269PubMed:15451426}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 13 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0040008 regulation of growth
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR013907 Sds3-like
PFAM PF08598
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5PSV4
PhosphoSite PhosphoSite-Q5PSV4
TrEMBL B3KU43
UniProt Splice Variant
Entrez Gene 84312
UniGene Hs.525299
RefSeq NP_115728
HUGO HGNC:20512
OMIM
CCDS CCDS32066
HPRD 16564
IMGT
EMBL AK096496 AK315424 AL162311 AY827074 BC006250
GenPept AAH06250 AAV83797 BAG37812 BAG53305

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca