Homo sapiens Protein: PGA3
Summary
InnateDB Protein IDBP-49780.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PGA3
Protein Name pepsinogen 3, group I (pepsinogen A)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000322192
InnateDB Gene IDBG-304133 (PGA3)
Protein Structure
UniProt Annotation
Function Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0007586 digestion
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR001461 Aspartic peptidase
IPR012848 Aspartic peptidase, N-terminal
IPR021109 Aspartic peptidase domain
PFAM PF00026
PF07966
PRINTS PR00792
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P0DJD8
PhosphoSite PhosphoSite-P0DJD8
TrEMBL F5H842
UniProt Splice Variant
Entrez Gene 643834
UniGene Hs.715019
RefSeq NP_001073275
HUGO HGNC:8885
OMIM 169700
CCDS CCDS31574
HPRD
IMGT
EMBL AK125628 AK312941 AP000437 AP003037 BC171815
GenPept AAI71815 BAG35783 BAG54225