Version 5.4
Homo sapiens Protein: PCDHB3
Summary
InnateDB Protein IDBP-49885.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCDHB3
Protein Name protocadherin beta 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000231130
InnateDB Gene IDBG-49883 (PCDHB3)
Protein Structure
UniProt Annotation
Function Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Subcellular Localization Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion
GO:0007268 synaptic transmission
GO:0007399 nervous system development
GO:0007416 synapse assembly
GO:0016339 calcium-dependent cell-cell adhesion
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002126 Cadherin
IPR013164 Cadherin, N-terminal
IPR015919 Cadherin-like
PFAM PF00028
PF08266
PRINTS PR00205
PIRSF
SMART SM00112
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y5E6
PhosphoSite PhosphoSite-Q9Y5E6
TrEMBL
UniProt Splice Variant
Entrez Gene 56132
UniGene Hs.708778
RefSeq NP_061760
HUGO HGNC:8688
OMIM 606329
CCDS CCDS4245
HPRD 08398
IMGT
EMBL AF152496 AF217755 AK313451 CH471062
GenPept AAD43757 AAK51622 BAG36239 EAW61981

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca