Version 5.4
Homo sapiens Protein: PCDHGC3
Summary
InnateDB Protein IDBP-50434.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCDHGC3
Protein Name protocadherin gamma subfamily C, 3
Synonyms PC43; PCDH-GAMMA-C3; PCDH2;
Species Homo sapiens
Ensembl Protein ENSP00000312070
InnateDB Gene IDBG-408922 (PCDHGC3)
Protein Structure
UniProt Annotation
Function Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Subcellular Localization Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
GO:0016339 calcium-dependent cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002126 Cadherin
IPR013164 Cadherin, N-terminal
IPR015919 Cadherin-like
PFAM PF00028
PF08266
PRINTS PR00205
PIRSF
SMART SM00112
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UN70
PhosphoSite PhosphoSite-Q9UN70
TrEMBL Q9UKW1
UniProt Splice Variant
Entrez Gene 5098
UniGene
RefSeq NP_002579
HUGO HGNC:8716
OMIM 603627
CCDS CCDS4261
HPRD 04693
IMGT
EMBL AF052683 AF052684 AF052685 AF119570 AF152337 AF152524 BC004321 BC019299 BC026218 L11371 L11372 L11373
GenPept AAA36420 AAA36421 AAA75391 AAC08350 AAD43731 AAD43784 AAF03087 AAH04321 AAH19299 AAH26218

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca