Version 5.4
Homo sapiens Protein: NAA50
Summary
InnateDB Protein IDBP-50469.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NAA50
Protein Name N(alpha)-acetyltransferase 50, NatE catalytic subunit
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000240922
InnateDB Gene IDBG-50467 (NAA50)
Protein Structure
UniProt Annotation
Function Probable catalytic component of the NAA11-NAA15 complex which displays alpha (N-terminal) acetyltransferase activity. {ECO:0000269PubMed:16507339}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:16507339}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 11 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004596 peptide alpha-N-acetyltransferase activity
GO:0005515 protein binding
GO:0008080 N-acetyltransferase activity
GO:0010485 H4 histone acetyltransferase activity
GO:0052858 peptidyl-lysine N-acetyltransferase activity
Biological Process
GO:0006474 N-terminal protein amino acid acetylation
GO:0008152 metabolic process
GO:0043967 histone H4 acetylation
GO:0071962 mitotic sister chromatid cohesion, centromeric
Cellular Component
GO:0005737 cytoplasm
GO:0031415 NatA complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000182 GNAT domain
IPR016181 Acyl-CoA N-acyltransferase
PFAM PF00583
PF13302
PF13508
PF13673
PF13718
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9GZZ1
PhosphoSite PhosphoSite-Q9GZZ1
TrEMBL B0AZT5
UniProt Splice Variant
Entrez Gene 80218
UniGene Hs.608460
RefSeq NP_079422
HUGO HGNC:29533
OMIM 610834
CCDS CCDS2975
HPRD 14350
IMGT
EMBL AC108693 AK023090 AK023256 AK296456 AK315876 BC012731 CH471052 CR749314
GenPept AAH12731 BAB14397 BAB14490 BAF98767 BAG59104 CAH18169 EAW79629 EAW79630

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca