InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CRIPT

Summary

InnateDB Protein

IDBP-50562.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CRIPT

Protein Name

cysteine-rich PDZ-binding protein

Synonyms

SSMDF;

Species

Homo sapiens

Ensembl Protein

ENSP00000238892

InnateDB Gene

IDBG-50558 (CRIPT)

Protein Structure

UniProt Annotation

Function

Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Cell projection, dendritic spine {ECO:0000250}. Note=Colocalizes with DLG4 in asymmetric synapses. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	7 [view]
Protein-DNA	2 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008017	microtubule binding
GO:0030165	PDZ domain binding
GO:0032403	protein complex binding

Biological Process

GO:0031122	cytoplasmic microtubule organization
GO:0035372	protein localization to microtubule
GO:0045184	establishment of protein localization
GO:1902897	regulation of postsynaptic density protein 95 clustering

Cellular Component

GO:0005737	cytoplasm
GO:0014069	postsynaptic density
GO:0030054	cell junction
GO:0030425	dendrite
GO:0043025	neuronal cell body
GO:0043197	dendritic spine
GO:0043198	dendritic shaft