InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TUBGCP3

Summary

InnateDB Protein

IDBP-51670.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TUBGCP3

Protein Name

tubulin, gamma complex associated protein 3

Synonyms

104p; GCP3; Grip104; SPBC98; Spc98; Spc98p;

Species

Homo sapiens

Ensembl Protein

ENSP00000261965

InnateDB Gene

IDBG-51668 (TUBGCP3)

Protein Structure

UniProt Annotation

Function

Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.

Subcellular Localization

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Disease Associations

Tissue Specificity

Ubiquitously expressed.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 132 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	132 [view]
Protein-Protein	130 [view]
Protein-DNA	1 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005198	structural molecule activity
GO:0005200	structural constituent of cytoskeleton
GO:0005515	protein binding
GO:0043015	gamma-tubulin binding

Biological Process

GO:0000086	G2/M transition of mitotic cell cycle
GO:0000226	microtubule cytoskeleton organization
GO:0000278	mitotic cell cycle
GO:0007020	microtubule nucleation
GO:0007338	single fertilization

Cellular Component

GO:0000922	spindle pole
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005814	centriole
GO:0005815	microtubule organizing center
GO:0005819	spindle
GO:0005827	polar microtubule
GO:0005829	cytosol
GO:0016020	membrane