InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: YIPF5

Summary

InnateDB Protein

IDBP-51789.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

YIPF5

Protein Name

Yip1 domain family, member 5

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000274496

InnateDB Gene

IDBG-51787 (YIPF5)

Protein Structure

UniProt Annotation

Function

Plays a role in transport between endoplasmic reticulum and Golgi. {ECO:0000269PubMed:11489904, ECO:0000269PubMed:15611160}.

Subcellular Localization

Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, Golgi stack membrane; Multi- pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle. Note=Enriched at the endoplasmic reticulum exit sites. Incorporated into COPII coated vesicles.

Disease Associations

Tissue Specificity

Ubiquitously expressed. Highly expressed in coronary smooth muscles. {ECO:0000269PubMed:15922870}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.

Experimentally validated
Total	9 [view]
Protein-Protein	8 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0015031	protein transport
GO:0016192	vesicle-mediated transport
GO:0060628	regulation of ER to Golgi vesicle-mediated transport

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030134	ER to Golgi transport vesicle
GO:0032580	Golgi cisterna membrane
GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
GO:0070971	endoplasmic reticulum exit site