InnateDB Protein
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IDBP-51863.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TRMT6
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Protein Name
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tRNA methyltransferase 6 homolog (S. cerevisiae)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000203001
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InnateDB Gene
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IDBG-51859 (TRMT6)
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Protein Structure
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Function |
Substrate-binding subunit of tRNA (adenine-N(1)-)- methyltransferase, which catalyzes the formation of N(1)- methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. {ECO:0000269PubMed:16043508}.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed in brain, liver, testis and ovary. {ECO:0000269PubMed:10574461}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
12
[view]
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Protein-Protein |
11
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007316
Eukaryotic initiation factor 3, gamma subunit
IPR017423
tRNA (adenine-N(1)-)-methyltransferase, non-catalytic TRM6 subunit
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PFAM |
PF04189
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PRINTS |
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PIRSF |
PIRSF038170
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9UJA5
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PhosphoSite |
PhosphoSite-Q9UJA5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
51605
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UniGene |
Hs.128791
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RefSeq |
NP_057023
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HUGO |
HGNC:20900
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OMIM |
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CCDS |
CCDS13093
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HPRD |
13027
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IMGT |
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EMBL |
AB032979
AF132943
AK000613
AK300812
AL035461
BC001262
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GenPept |
AAD27718
AAH01262
BAA86467
BAG62468
CAB55274
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