Version 5.4
Homo sapiens Protein: GRXCR2
Summary
InnateDB Protein IDBP-51890.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GRXCR2
Protein Name glutaredoxin, cysteine rich 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000367214
InnateDB Gene IDBG-51888 (GRXCR2)
Protein Structure
UniProt Annotation
Function Could play a role in maintaining cochlear stereocilia bundles that are involved in sound detection. {ECO:0000269PubMed:24619944}.
Subcellular Localization Cell projection, stereocilium {ECO:0000250}.
Disease Associations Deafness, autosomal recessive, 101 (DFNB101) [MIM:615837]: A form of non-syndromic deafness characterized by bilateral, moderate to severe hearing loss. Vestibular function is unaffected. {ECO:0000269PubMed:24619944}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0031072 heat shock protein binding
GO:0051082 unfolded protein binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A6NFK2
PhosphoSite PhosphoSite-A6NFK2
TrEMBL
UniProt Splice Variant
Entrez Gene 643226
UniGene Hs.570895
RefSeq NP_001073985
HUGO HGNC:33862
OMIM 615762
CCDS CCDS34263
HPRD
IMGT
EMBL AC011359
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca