Version 5.4
Homo sapiens Protein: ACOT9
Summary
InnateDB Protein IDBP-52134.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACOT9
Protein Name acyl-CoA thioesterase 9
Synonyms ACATE2; MT-ACT48; MTACT48;
Species Homo sapiens
Ensembl Protein ENSP00000368597
InnateDB Gene IDBG-52124 (ACOT9)
Protein Structure
UniProt Annotation
Function Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs.
Subcellular Localization Mitochondrion {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003986 acetyl-CoA hydrolase activity
Biological Process
GO:0006637 acyl-CoA metabolic process
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro IPR006683 Thioesterase superfamily
IPR029069 HotDog domain
PFAM PF03061
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y305
PhosphoSite PhosphoSite-Q9Y305
TrEMBL Q9H2R8
UniProt Splice Variant
Entrez Gene 23597
UniGene Hs.660973
RefSeq XP_005274528
HUGO HGNC:17152
OMIM 300862
CCDS
HPRD 06438
IMGT
EMBL AC093011 AC131011 AF132950 AF241787 AK024337 BC136671 BC144360 BX648512 CH471074
GenPept AAD27725 AAG44475 AAI36672 AAI44361 BAG51291 EAW98998

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca