Homo sapiens Protein: MIA
Summary
InnateDB Protein IDBP-52199.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MIA
Protein Name melanoma inhibitory activity
Synonyms CD-RAP;
Species Homo sapiens
Ensembl Protein ENSP00000263369
InnateDB Gene IDBG-727669 (MIA)
Protein Structure
UniProt Annotation
Function Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity All malignant melanoma cell lines tested and infrequently in glioma cell lines.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008083 growth factor activity
Biological Process
GO:0007160 cell-matrix adhesion
GO:0008283 cell proliferation
GO:0030198 extracellular matrix organization
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR001452 SH3 domain
IPR011511 Variant SH3 domain
PFAM PF00018
PF14604
PF07653
PRINTS PR00452
PIRSF
SMART SM00326
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q16674
PhosphoSite PhosphoSite-Q16674
TrEMBL M0R343
UniProt Splice Variant
Entrez Gene 8190
UniGene Hs.646364
RefSeq NP_006524
HUGO HGNC:7076
OMIM 601340
CCDS CCDS12566
HPRD 03216
IMGT
EMBL AC020945 AC098779 BC005910 BT007044 CH471126 CR541648 X75450 X84707
GenPept AAH05910 AAP35693 CAA53203 CAA59195 CAG46449 EAW56997 EAW56998 EAW56999