Homo sapiens Protein: CYP2A7 | |||||||||||||
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Summary | |||||||||||||
InnateDB Protein | IDBP-52294.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | CYP2A7 | ||||||||||||
Protein Name | cytochrome P450, family 2, subfamily A, polypeptide 7 | ||||||||||||
Synonyms | CPA7; CPAD; CYP2A; CYPIIA7; P450-IIA4; | ||||||||||||
Species | Homo sapiens | ||||||||||||
Ensembl Protein | ENSP00000301146 | ||||||||||||
InnateDB Gene | IDBG-52290 (CYP2A7) | ||||||||||||
Protein Structure | |||||||||||||
UniProt Annotation | |||||||||||||
Function | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | ||||||||||||
Subcellular Localization | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. | ||||||||||||
Disease Associations | |||||||||||||
Tissue Specificity | |||||||||||||
Comments | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||
PDB ID | |||||||||||||
InterPro |
IPR001128
Cytochrome P450 IPR002401 Cytochrome P450, E-class, group I IPR002403 Cytochrome P450, E-class, group IV IPR008067 Cytochrome P450, E-class, group I, CYP2A-like IPR008068 Cytochrome P450, E-class, group I, CYP2B-like |
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PFAM |
PF00067
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PRINTS |
PR00385
PR00463 PR00465 PR01684 PR01685 |
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PIRSF | |||||||||||||
SMART | |||||||||||||
TIGRFAMs | |||||||||||||
Post-translational Modifications | |||||||||||||
Modification | |||||||||||||
Cross-References | |||||||||||||
SwissProt | P20853 | ||||||||||||
PhosphoSite | PhosphoSite-P20853 | ||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 1549 | ||||||||||||
UniGene | |||||||||||||
RefSeq | NP_000755 | ||||||||||||
HUGO | HGNC:2611 | ||||||||||||
OMIM | 608054 | ||||||||||||
CCDS | CCDS12569 | ||||||||||||
HPRD | 07453 | ||||||||||||
IMGT | |||||||||||||
EMBL | AC008537 M33317 U22029 | ||||||||||||
GenPept | AAA52138 AAB40520 | ||||||||||||