InnateDB Protein
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IDBP-52357.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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IKBIP
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Protein Name
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IKBKB interacting protein
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000299157
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InnateDB Gene
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IDBG-52353 (IKBIP)
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Protein Structure
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Function |
Target of p53/TP53 with pro-apoptotic function. {ECO:0000269PubMed:15389287}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000269PubMed:15389287}; Single-pass membrane protein {ECO:0000269PubMed:15389287}. Note=Isoform 4 deletion of the hydrophobic, or transmembrane region between AA 45-63 results in uniform distribution throughout the cell, suggesting that this region is responsible for endoplasmic reticulum localization.
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Disease Associations |
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Tissue Specificity |
Expressed in vein endothelial cells. Isoform 4 is expressed in lung, kidney, spleen, thymus and skeletal muscle. {ECO:0000269PubMed:15389287}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
21
[view]
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Protein-Protein |
21
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q70UQ0
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PhosphoSite |
PhosphoSite-Q70UQ0
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
121457
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UniGene |
Hs.619381
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RefSeq |
NP_710154
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HUGO |
HGNC:26430
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OMIM |
609861
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CCDS |
CCDS9068
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HPRD |
08092
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IMGT |
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EMBL |
AJ539425
AJ539426
AJ539427
AK055613
AK123069
BC029415
BC051372
BC058933
CH471054
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GenPept |
AAH29415
AAH51372
AAH58933
BAB70970
BAC85528
CAD62380
CAD62381
CAD62382
CAD62383
EAW97601
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