Version 5.4
Homo sapiens Protein: HRASLS5
Summary
InnateDB Protein IDBP-52446.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HRASLS5
Protein Name HRAS-like suppressor family, member 5
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000301790
InnateDB Gene IDBG-52444 (HRASLS5)
Protein Structure
UniProt Annotation
Function catalyzes N-acylation of phosphatidylethanolamine (PE) to generate N-Acylphosphatidylethanolamine (NAPE) a precursor of bioactive N-acylethanolamines, including the endocannabinoid anandamide. {ECO:0000269PubMed:19000777}.
Subcellular Localization
Disease Associations
Tissue Specificity Highest expression level in testis and pancreas.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0008152 metabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR007053 LRAT-like domain
PFAM PF04970
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96KN8
PhosphoSite PhosphoSite-
TrEMBL F5H4Q3
UniProt Splice Variant
Entrez Gene 117245
UniGene Hs.607886
RefSeq NP_473449
HUGO HGNC:24978
OMIM 611474
CCDS CCDS8044
HPRD 13672
IMGT
EMBL AB298804 AJ416558 AP000484 AP001591 CH471076
GenPept BAH08633 CAC94942 EAW74150

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca