Version 5.4
Homo sapiens Protein: HSPBAP1
Summary
InnateDB Protein IDBP-52734.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSPBAP1
Protein Name HSPB (heat shock 27kDa) associated protein 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000302562
InnateDB Gene IDBG-52732 (HSPBAP1)
Protein Structure
UniProt Annotation
Function May play a role in cellular stress response. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations Note=A chromosomal aberration involving HSPBAP1 has been found in a family with renal carcinoma. Translocation t(2;3)(q35;q21) with the putative pseudogene DIRC3. Produces a hybrid mRNA encoding a truncated HSPBAP1 lacking the first 36 amino acids.
Tissue Specificity Widely expressed. {ECO:0000269PubMed:11978969}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR003347 JmjC domain
IPR013296 HSPB1-associated protein 1
PFAM PF02373
PF08007
PRINTS PR01886
PIRSF
SMART SM00558
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96EW2
PhosphoSite PhosphoSite-Q96EW2
TrEMBL Q9H641
UniProt Splice Variant
Entrez Gene 79663
UniGene Hs.29169
RefSeq NP_078886
HUGO HGNC:16389
OMIM 608263
CCDS CCDS3017
HPRD 12197
IMGT
EMBL AF400663 AK026276 AK096705 BC011897 BC017763 BC063629
GenPept AAH11897 AAH17763 AAH63629 AAM64044 BAB15425 BAC04847

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca