InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: COX8A

Summary

InnateDB Protein

IDBP-52977.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

COX8A

Protein Name

cytochrome c oxidase subunit VIIIA (ubiquitous)

Synonyms

COX; COX8; COX8-2; COX8L; VIII; VIII-L;

Species

Homo sapiens

Ensembl Protein

ENSP00000321260

InnateDB Gene

IDBG-52975 (COX8A)

Protein Structure

UniProt Annotation

Function

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Subcellular Localization

Mitochondrion inner membrane.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	2 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004129	cytochrome-c oxidase activity

Biological Process

GO:0006091	generation of precursor metabolites and energy
GO:0022904	respiratory electron transport chain
GO:0044237	cellular metabolic process
GO:0044281	small molecule metabolic process
GO:1902600	hydrogen ion transmembrane transport

Cellular Component

GO:0005743	mitochondrial inner membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003205 Cytochrome c oxidase, subunit 8

PFAM

PF02285

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P10176

PhosphoSite

PhosphoSite-

TrEMBL

Q53XN1

UniProt Splice Variant

Entrez Gene

1351

UniGene

Hs.433901

RefSeq

NP_004065

HUGO

HGNC:2294

OMIM

123870

CCDS

CCDS8054

HPRD

00468

IMGT

EMBL

AK311934 BC063025 BT009803 CH471076 CR407687 J04823

GenPept

AAA99313 AAH63025 AAP88805 BAG34875 CAG28615 EAW74186