Homo sapiens Protein: FLRT1
Summary
InnateDB Protein IDBP-53076.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FLRT1
Protein Name fibronectin leucine rich transmembrane protein 1
Synonyms SPG68;
Species Homo sapiens
Ensembl Protein ENSP00000246841
InnateDB Gene IDBG-53074 (FLRT1)
Protein Structure
UniProt Annotation
Function May have a function in cell adhesion and/or receptor signaling.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in kidney and brain. {ECO:0000269PubMed:10644439}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005057 receptor signaling protein activity
GO:0005515 protein binding
GO:0030674 protein binding, bridging
Biological Process
GO:0007155 cell adhesion
GO:0008150 biological_process
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0005887 integral component of plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR000372 Leucine-rich repeat-containing N-terminal
IPR000483 Cysteine-rich flanking region, C-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
IPR003961 Fibronectin, type III
PFAM PF01462
PF01463
PF00560
PF13504
PF13855
PF00041
PF01108
PRINTS
PIRSF
SMART SM00013
SM00082
SM00369
SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NZU1
PhosphoSite PhosphoSite-Q9NZU1
TrEMBL O43408
UniProt Splice Variant
Entrez Gene 23769
UniGene Hs.584876
RefSeq NP_037412
HUGO HGNC:3760
OMIM 604806
CCDS CCDS8057
HPRD 05311
IMGT
EMBL AF007139 AF169675 AK289931 AP006333 AY358308 BC018370 CH471076
GenPept AAC19151 AAF28459 AAH18370 AAQ88675 BAF82620 EAW74194