InnateDB Protein
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IDBP-5311.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CTAGE5
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Protein Name
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CTAGE family, member 5
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000339286
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InnateDB Gene
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IDBG-5307 (CTAGE5)
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Protein Structure
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Function |
Tumor-associated antigen.
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Subcellular Localization |
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Disease Associations |
Note=Autoantibodies against CTAGE5 are present in several cancer types, including benign meningioma and cutaneous T-cell lymphoma (CTCL).
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Tissue Specificity |
Isoform 5A is expressed only in testis (at the protein level). Other isoforms are expressed in several other normal tissues, including brain, muscle and cranial skin. Isoform 5A (at protein level) and isoform 5B are expressed in cutaneous T- cell lymphoma (CTCL) cell lines, colorectal carcinomas, breast carcinomas and melanoma. Isoform 5B, but not isoform 5A, is expressed in head and neck squamous cell carcinoma.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
6
[view]
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Protein-Protein |
6
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0008047
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enzyme activator activity
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Biological Process |
GO:0043085
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positive regulation of catalytic activity
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O15320
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PhosphoSite |
PhosphoSite-O15320
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
4253
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UniGene |
Hs.540038
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RefSeq |
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HUGO |
HGNC:7057
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OMIM |
602132
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CCDS |
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HPRD |
03680
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IMGT |
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EMBL |
AF338233
AF338234
AK091252
AK298935
AL132639
AL157791
BC051363
BC064355
BX640994
CH471078
U73682
U94780
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GenPept |
AAB86589
AAB86593
AAH51363
AAH64355
AAN77610
AAN77611
BAG52318
BAG61038
CAE45997
EAW65808
EAW65812
EAW65813
EAW65814
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