Mus musculus Protein: Adarb2
Summary
InnateDB Protein IDBP-531552.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adarb2
Protein Name adenosine deaminase, RNA-specific, B2
Synonyms Adar3; RED2;
Species Mus musculus
Ensembl Protein ENSMUSP00000115148
InnateDB Gene IDBG-129047 (Adarb2)
Protein Structure
UniProt Annotation
Function Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Brain specific.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004000 adenosine deaminase activity
GO:0046872 metal ion binding
Biological Process
GO:0006396 RNA processing
GO:0006397 mRNA processing
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:2151118
InterPro IPR002466 Adenosine deaminase/editase
IPR014720 Double-stranded RNA-binding domain
PFAM PF02137
PF00035
PRINTS
PIRSF
SMART SM00552
SM00358
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JI20
PhosphoSite PhosphoSite-Q9JI20
TrEMBL
UniProt Splice Variant
Entrez Gene 94191
UniGene Mm.449008
RefSeq XP_006516574
MGI ID
MGI Symbol Adarb2
OMIM
CCDS CCDS26231
HPRD
IMGT
EMBL AF232942 AF270495 AK033916 AK139079 AK139273 BC052426
GenPept AAF76894 AAF78580 AAH52426 BAC28513 BAE23882 BAE23939