Version 5.4
Mus musculus Protein: Gpc2
Summary
InnateDB Protein IDBP-531604.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpc2
Protein Name glypican 2 (cerebroglycan)
Synonyms 2410016G05Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000124459
InnateDB Gene IDBG-206089 (Gpc2)
Protein Structure
UniProt Annotation
Function Cell surface proteoglycan that bears heparan sulfate. May fulfill a function related to the motile behaviors of developing neurons (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}; Extracellular side {ECO:0000250}.Secreted glypican-2: Secreted, extracellular space {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0043395 heparan sulfate proteoglycan binding
Biological Process
GO:0007224 smoothened signaling pathway
GO:0030182 neuron differentiation
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
GO:0005796 Golgi lumen
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0031225 anchored component of membrane
Protein Structure and Domains
PDB ID MGI:1919201
InterPro IPR001863 Glypican
PFAM PF01153
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BKV1
PhosphoSite PhosphoSite-Q8BKV1
TrEMBL M0QWK4
UniProt Splice Variant
Entrez Gene 71951
UniGene Mm.77066
RefSeq NP_766000
MGI ID
MGI Symbol Gpc2
OMIM
CCDS CCDS19799
HPRD
IMGT
EMBL AC159257 AK049639 BC083180 BC128572
GenPept AAH83180 AAI28573 BAC33852

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca