InnateDB Protein
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IDBP-531748.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Pgap3
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Protein Name
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post-GPI attachment to proteins 3
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000119668
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InnateDB Gene
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IDBG-210579 (Pgap3)
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Protein Structure
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Function |
Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins. Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI (By similarity). {ECO:0000250}.
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Subcellular Localization |
Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Mainly localizes to Golgi apparatus. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
Accession |
GO Term |
GO:0016788
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hydrolase activity, acting on ester bonds
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2444461
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InterPro |
IPR007217
Per1-like
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PFAM |
PF04080
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
A2A559
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
320655
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UniGene |
Mm.86519
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RefSeq |
XP_006533612
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MGI ID |
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MGI Symbol |
Pgap3
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AK170817
AL591390
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GenPept |
BAE42049
CAM22011
CAM22012
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