Version 5.4
Mus musculus Protein: Sfxn4
Summary
InnateDB Protein IDBP-531852.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sfxn4
Protein Name sideroflexin 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000118743
InnateDB Gene IDBG-181797 (Sfxn4)
Protein Structure
UniProt Annotation
Function Potential iron transporter.
Subcellular Localization Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Largely restricted to kidney, brain and heart. {ECO:0000269PubMed:11274051}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008324 cation transmembrane transporter activity
Biological Process
GO:0006812 cation transport
GO:0008150 biological_process
GO:0055072 iron ion homeostasis
GO:0055085 transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID MGI:2137680
InterPro IPR004686 Tricarboxylate/iron carrier
PFAM PF03820
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q925N1
PhosphoSite PhosphoSite-Q925N1
TrEMBL
UniProt Splice Variant
Entrez Gene 94281
UniGene Mm.48179
RefSeq NP_444428
MGI ID
MGI Symbol Sfxn4
OMIM
CCDS CCDS29943
HPRD
IMGT
EMBL AC102432 AC163019 AF325263 BC089535
GenPept AAH89535 AAK39431

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca