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InnateDB Protein
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IDBP-532036.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Dusp10
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Protein Name
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dual specificity phosphatase 10
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Synonyms
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2610306G15Rik; AI158871; MKP-5; MKP5;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000121433
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InnateDB Gene
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IDBG-207813 (Dusp10)
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Protein Structure
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| Function |
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
2
[view]
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| Protein-Protein |
2
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
12 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0008138
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protein tyrosine/serine/threonine phosphatase activity
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GO:0033549
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MAP kinase phosphatase activity
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| Biological Process |
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GO:0000188
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inactivation of MAPK activity
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GO:0002819
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regulation of adaptive immune response
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GO:0006470
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protein dephosphorylation
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GO:0032496
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response to lipopolysaccharide
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GO:0032873
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negative regulation of stress-activated MAPK cascade
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GO:0043508
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negative regulation of JUN kinase activity
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GO:0045087
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innate immune response (InnateDB)
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GO:0045088
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regulation of innate immune response
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GO:0046329
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negative regulation of JNK cascade
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GO:0048709
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oligodendrocyte differentiation
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GO:0060266
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negative regulation of respiratory burst involved in inflammatory response
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| Cellular Component |
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| PDB ID |
MGI:1927070
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| InterPro |
IPR001762
Blood coagulation inhibitor, Disintegrin
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| PFAM |
PF00200
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| PRINTS |
PR00289
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| PIRSF |
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| SMART |
SM00050
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
D3Z2S1
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| UniProt Splice Variant |
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| Entrez Gene |
63953
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| UniGene |
Mm.474140
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| RefSeq |
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| MGI ID |
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| MGI Symbol |
Dusp10
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
AC107743
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| GenPept |
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Version 5.4