InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tfeb

Summary

InnateDB Protein

IDBP-532157.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tfeb

Protein Name

transcription factor EB

Synonyms

bHLHe35; Tcfeb;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119508

InnateDB Gene

IDBG-189516 (Tfeb)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	2 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0044212	transcription regulatory region DNA binding
GO:0046983	protein dimerization activity

Biological Process

GO:0001892	embryonic placenta development
GO:0006959	humoral immune response
GO:0007040	lysosome organization
GO:0010508	positive regulation of autophagy
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:103270

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z219

UniProt Splice Variant

Entrez Gene

21425

UniGene

Mm.2305

RefSeq

MGI ID

MGI Symbol

Tfeb

OMIM

CCDS

HPRD

IMGT

EMBL

AC113536 AC124830

GenPept