InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mamstr

Summary

InnateDB Protein

IDBP-532410.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mamstr

Protein Name

MEF2 activating motif and SAP domain containing transcriptional regulator

Synonyms

2810022D01Rik; 5430432N15Rik; AW743872; Mastr;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000114686

InnateDB Gene

IDBG-183936 (Mamstr)

Protein Structure

UniProt Annotation

Function

Transcriptional coactivator. Stimulates the transcriptional activity of MEF2C. Stimulates MYOD1 activity in part via MEF2, resulting in an enhancement of skeletal muscle differentiation. {ECO:0000269PubMed:16818234}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:16818234}.

Disease Associations

Tissue Specificity

Expressed in skeletal muscle, brain, placenta and spleen. {ECO:0000269PubMed:16818234}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001076	RNA polymerase II transcription factor binding transcription factor activity
GO:0003676	nucleic acid binding
GO:0005515	protein binding

Biological Process

GO:0006366	transcription from RNA polymerase II promoter
GO:0010831	positive regulation of myotube differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter