InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Bicc1

Summary

InnateDB Protein

IDBP-532457.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bicc1

Protein Name

bicaudal C homolog 1 (Drosophila)

Synonyms

Bic-C; bpk; jcpk;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119137

InnateDB Gene

IDBG-161518 (Bicc1)

Protein Structure

UniProt Annotation

Function

Putative RNA-binding protein. May be involved in regulating gene expression during embryonic development.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:19324013}.

Disease Associations

Tissue Specificity

In the adult, predominantly expressed in heart and kidney. In 8 week old mice, expressed in growing primary oocytes and in the stromal cells of the theca. {ECO:0000269PubMed:11231089}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding

Biological Process

GO:0007275	multicellular organismal development
GO:0090090	negative regulation of canonical Wnt signaling pathway

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

MGI:1933388

InterPro

IPR001660 Sterile alpha motif domain
IPR004087 K Homology domain
IPR004088 K Homology domain, type 1
IPR011510 Sterile alpha motif, type 2
IPR013761 Sterile alpha motif/pointed domain
IPR021129 Sterile alpha motif, type 1

PFAM

PF00013
PF13014
PF07647
PF00536

PRINTS

PIRSF

SMART

SM00454
SM00322

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q99MQ1

PhosphoSite

PhosphoSite-Q99MQ1

TrEMBL

UniProt Splice Variant

Entrez Gene

83675

UniGene

Mm.458090

RefSeq

MGI ID

MGI Symbol

Bicc1

OMIM

CCDS

HPRD

IMGT

EMBL

AF319464 AK089066 BC062174 BC111523

GenPept

AAH62174 AAI11524 AAK27347 BAC40732