InnateDB Protein
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IDBP-532515.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Tlcd1
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Protein Name
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TLC domain containing 1
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000114202
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InnateDB Gene
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IDBG-202299 (Tlcd1)
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Protein Structure
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Function |
Calcium channel facilitator that increases calcium flux by generating a larger window current and slowing inactivation of the L-type CACNA1C/CaV1.2 channel. Regulation of intracellular calcium by Calfacilitin is required for neural plate formation (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
0
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Protein-DNA |
1
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1915572
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InterPro |
IPR006634
TRAM/LAG1/CLN8 homology domain
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PFAM |
PF03798
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PRINTS |
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PIRSF |
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SMART |
SM00724
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TIGRFAMs |
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Modification |
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SwissProt |
Q99JT6
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
68385
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UniGene |
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RefSeq |
NP_080984
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MGI ID |
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MGI Symbol |
Tlcd1
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OMIM |
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CCDS |
CCDS25092
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HPRD |
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IMGT |
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EMBL |
AK002703
AK046577
AK161721
AK165432
AL591070
BC005702
BC039182
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GenPept |
AAH05702
AAH39182
BAB22297
BAE20654
BAE36548
BAE38185
CAI24331
CAI24332
CAI24333
CAI24334
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