Mus musculus Protein: Tmeff1
Summary
InnateDB Protein IDBP-532543.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmeff1
Protein Name transmembrane protein with EGF-like and two follistatin-like domains 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000115841
InnateDB Gene IDBG-146698 (Tmeff1)
Protein Structure
UniProt Annotation
Function May inhibit NODAL and BMP signaling during neural patterning. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in brain, neurointermediate lobe, pars distalis, pancreas, ovary and testis. {ECO:0000269PubMed:11025219, ECO:0000269PubMed:11165370}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007275 multicellular organismal development
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1926810
InterPro IPR000742 Epidermal growth factor-like domain
IPR002350 Kazal domain
PFAM PF00008
PF00050
PF07648
PRINTS
PIRSF
SMART SM00181
SM00280
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PFE7
PhosphoSite PhosphoSite-Q6PFE7
TrEMBL
UniProt Splice Variant
Entrez Gene 230157
UniGene Mm.422686
RefSeq
MGI ID
MGI Symbol Tmeff1
OMIM
CCDS CCDS18168
HPRD
IMGT
EMBL AJ400622 AK043792 AK079633 AL772151 AL807771 BC057598
GenPept AAH57598 BAC31655 BAC37709 CAB90827 CAM15043 CAM15044 CAM20710 CAM20711