InnateDB Protein
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IDBP-532568.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ramp2
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Protein Name
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receptor (calcitonin) activity modifying protein 2
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000122072
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InnateDB Gene
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IDBG-211974 (Ramp2)
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Protein Structure
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Function |
Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL. {ECO:0000269PubMed:10854696}.
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Subcellular Localization |
Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Ubiquitous. Expressed predominantly in embryonic brain, lung and gut and in adult heart, lung, skeletal muscle and brain. {ECO:0000269PubMed:10777702, ECO:0000269PubMed:10854696}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1859650
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InterPro |
IPR006985
Receptor activity modifying protein
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PFAM |
PF04901
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9WUP0
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PhosphoSite |
PhosphoSite-
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TrEMBL |
A8XY18
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UniProt Splice Variant |
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Entrez Gene |
54409
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UniGene |
Mm.481089
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RefSeq |
NP_062317
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MGI ID |
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MGI Symbol |
Ramp2
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OMIM |
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CCDS |
CCDS25457
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HPRD |
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IMGT |
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EMBL |
AF146523
AF209906
AJ250490
AK003810
AL590969
BC069992
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GenPept |
AAD35019
AAF21038
AAH69992
BAB23009
CAB59512
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