Version 5.4
Homo sapiens Protein: AVEN
Summary
InnateDB Protein IDBP-5326.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AVEN
Protein Name apoptosis, caspase activation inhibitor
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000306822
InnateDB Gene IDBG-5324 (AVEN)
Protein Structure
UniProt Annotation
Function Protects against apoptosis mediated by Apaf-1.
Subcellular Localization Endomembrane system; Peripheral membrane protein. Note=Associated with intracellular membranes.
Disease Associations
Tissue Specificity Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006915 apoptotic process
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005622 intracellular
GO:0012505 endomembrane system
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NQS1
PhosphoSite PhosphoSite-Q9NQS1
TrEMBL
UniProt Splice Variant
Entrez Gene 57099
UniGene Hs.555966
RefSeq NP_065104
HUGO HGNC:13509
OMIM 605265
CCDS CCDS10030
HPRD 05588
IMGT
EMBL AF283508 BC010488 BC063533
GenPept AAF91470 AAH10488 AAH63533

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca