InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Trim59

Summary

InnateDB Protein

IDBP-532709.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Trim59

Protein Name

tripartite motif-containing 59

Synonyms

2310035M22Rik; 2700022F13Rik; Mrf1; TSBF1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119748

InnateDB Gene

IDBG-151277 (Trim59)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

Biological Process

GO:0016567	protein ubiquitination
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling

Cellular Component

GO:0000151	ubiquitin ligase complex
GO:0005783	endoplasmic reticulum

Protein Structure and Domains

PDB ID

MGI:1914199

InterPro

IPR001841 Zinc finger, RING-type
IPR003613 U box domain
IPR018957 Zinc finger, C3HC4 RING-type

PFAM

PF13639
PF14634
PF04564
PF00097

PRINTS

PIRSF

SMART

SM00184
SM00504

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z1L3

UniProt Splice Variant

Entrez Gene

66949

UniGene

Mm.490341

RefSeq

MGI ID

MGI Symbol

Trim59

OMIM

CCDS

HPRD

IMGT

EMBL

AC122876

GenPept