InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cntn5

Summary

InnateDB Protein

IDBP-533225.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cntn5

Protein Name

contactin 5

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000124327

InnateDB Gene

IDBG-133869 (Cntn5)

Protein Structure

UniProt Annotation

Function

Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons (By similarity). Involved in neuronal activity in the auditory system. {ECO:0000250, ECO:0000269PubMed:12653969}.

Subcellular Localization

Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed in the nervous system. Preferentially expressed in the central auditory pathways. {ECO:0000269PubMed:12653969}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007155	cell adhesion
GO:0007605	sensory perception of sound

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0031225	anchored component of membrane

Protein Structure and Domains

PDB ID

MGI:3042287

InterPro

IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin

PFAM

PF00041
PF01108
PF07679
PF07686
PF00047

PRINTS

PIRSF

SMART

SM00408
SM00409
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P68500