Version 5.4
Mus musculus Protein: Scn1a
Summary
InnateDB Protein IDBP-533407.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Scn1a
Protein Name sodium channel, voltage-gated, type I, alpha
Synonyms B230332M13; Nav1.1;
Species Mus musculus
Ensembl Protein ENSMUSP00000116881
InnateDB Gene IDBG-175211 (Scn1a)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005248 voltage-gated sodium channel activity
Biological Process
GO:0001508 action potential
GO:0006814 sodium ion transport
GO:0007628 adult walking behavior
GO:0019227 neuronal action potential propagation
GO:0019228 neuronal action potential
GO:0035725 sodium ion transmembrane transport
GO:0042391 regulation of membrane potential
GO:0050884 neuromuscular process controlling posture
GO:0086010 membrane depolarization during action potential
Cellular Component
GO:0001518 voltage-gated sodium channel complex
GO:0014704 intercalated disc
GO:0016020 membrane
GO:0030315 T-tubule
GO:0030424 axon
GO:0033268 node of Ranvier
GO:0034706 sodium channel complex
GO:0043025 neuronal cell body
GO:0043194 axon initial segment
Protein Structure and Domains
PDB ID MGI:98246
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A2APX9
UniProt Splice Variant
Entrez Gene 20265
UniGene Mm.439704
RefSeq
MGI ID
MGI Symbol Scn1a
OMIM
CCDS
HPRD
IMGT
EMBL AL844526 AL928726
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca