Mus musculus Protein: Prdx4
Summary
InnateDB Protein IDBP-533421.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prdx4
Protein Name peroxiredoxin 4
Synonyms AOE372; Prx-iv; Prx4; TRANK;
Species Mus musculus
Ensembl Protein ENSMUSP00000122997
InnateDB Gene IDBG-181439 (Prdx4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 33 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016209 antioxidant activity
GO:0016491 oxidoreductase activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0007283 spermatogenesis
GO:0008584 male gonad development
GO:0019471 4-hydroxyproline metabolic process
GO:0022417 protein maturation by protein folding
GO:0030198 extracellular matrix organization
GO:0045454 cell redox homeostasis
GO:0055114 oxidation-reduction process
GO:0072593 reactive oxygen species metabolic process
GO:2000255 negative regulation of male germ cell proliferation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
Protein Structure and Domains
PDB ID MGI:1859815
InterPro IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
IPR012336 Thioredoxin-like fold
IPR013740 Redoxin
PFAM PF00578
PF13098
PF13192
PF13462
PF13905
PF08534
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B1AZS9
UniProt Splice Variant
Entrez Gene 53381
UniGene Mm.402154
RefSeq XP_006528973
MGI ID
MGI Symbol Prdx4
OMIM
CCDS
HPRD
IMGT
EMBL BX005263
GenPept