InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Alox5ap

Summary

InnateDB Protein

IDBP-533462.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Alox5ap

Protein Name

arachidonate 5-lipoxygenase activating protein

Synonyms

Flap;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119413

InnateDB Gene

IDBG-209378 (Alox5ap)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0042803	protein homodimerization activity
GO:0046982	protein heterodimerization activity
GO:0047485	protein N-terminus binding
GO:0050544	arachidonic acid binding

Biological Process

GO:0002540	leukotriene production involved in inflammatory response
GO:0002675	positive regulation of acute inflammatory response
GO:0019370	leukotriene biosynthetic process
GO:0070207	protein homotrimerization
GO:0071277	cellular response to calcium ion

Cellular Component

GO:0005634	nucleus
GO:0005635	nuclear envelope
GO:0005783	endoplasmic reticulum
GO:0005829	cytosol
GO:0031965	nuclear membrane

Protein Structure and Domains

PDB ID

MGI:107505

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z294

UniProt Splice Variant

Entrez Gene

11690

UniGene

RefSeq

MGI ID

MGI Symbol

Alox5ap

OMIM

CCDS

HPRD

IMGT

EMBL

AC122546 AC175377

GenPept