Version 5.4
Homo sapiens Protein: MAGEB18
Summary
InnateDB Protein IDBP-53355.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAGEB18
Protein Name melanoma antigen family B, 18
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000314543
InnateDB Gene IDBG-53353 (MAGEB18)
Protein Structure
UniProt Annotation
Function May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. {ECO:0000269PubMed:20864041}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR002190 MAGE protein
IPR021072 Melanoma associated antigen, MAGE, N-terminal
PFAM PF01454
PF12440
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96M61
PhosphoSite PhosphoSite-Q96M61
TrEMBL
UniProt Splice Variant
Entrez Gene 286514
UniGene Hs.350683
RefSeq NP_775970
HUGO HGNC:28515
OMIM
CCDS CCDS14216
HPRD 06647
IMGT
EMBL AC129850 AK057361 BC029525
GenPept AAH29525 BAB71450

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca