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InnateDB Protein
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IDBP-533577.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Arhgef1
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Protein Name
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Rho guanine nucleotide exchange factor (GEF) 1
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Synonyms
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Lbcl2; Lsc;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000114388
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InnateDB Gene
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IDBG-155851 (Arhgef1)
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Protein Structure
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| Function |
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
15
[view]
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| Protein-Protein |
15
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
19 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0005089
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Rho guanyl-nucleotide exchange factor activity
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GO:0005515
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protein binding
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| Biological Process |
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GO:0032319
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regulation of Rho GTPase activity
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GO:0038032
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termination of G-protein coupled receptor signaling pathway
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| Cellular Component |
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| PDB ID |
MGI:1353510
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| InterPro |
IPR015212
Regulator of G protein signalling-like domain
IPR016137
Regulator of G protein signalling superfamily
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| PFAM |
PF09128
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| PRINTS |
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| PIRSF |
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| SMART |
SM00315
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
D3YVJ9
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| UniProt Splice Variant |
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| Entrez Gene |
16801
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| UniGene |
Mm.407747
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| RefSeq |
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| MGI ID |
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| MGI Symbol |
Arhgef1
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
AC161441
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| GenPept |
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Version 5.4