InnateDB Protein
|
IDBP-533578.3
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Samd4
|
Protein Name
|
sterile alpha motif domain containing 4
|
Synonyms
|
1700024G08Rik; 1700111L17Rik; 4933436G17Rik; Samd4a; Smaug; Smaug1;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000115569
|
InnateDB Gene
|
IDBG-153990 (Samd4)
|
Protein Structure
|
|
Function |
Acts as a translational repressor of SRE-containing messengers. {ECO:0000250}.
|
Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:16221671}. Cell projection, dendrite {ECO:0000269PubMed:16221671}. Cell junction, synapse, synaptosome {ECO:0000269PubMed:16221671}. Note=Colocalizes throughout the cytoplasm in granules with polyadenylated RNAs, PABPC1 and STAU1. Also frequently colocalizes in cytoplasmic stress granule-like foci with ELAVL1, TIA1 and TIAL1. Shuttles between the nucleus and the cytoplasm in a CRM1- dependent manner (By similarity). Enriched in synaptoneurosomes. {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
Expressed in brain (at protein level). {ECO:0000269PubMed:16221671}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
|
Predicted by orthology |
Total |
1 [view]
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0030371
|
translation repressor activity
|
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:1921730
|
InterPro |
|
PFAM |
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q8CBY1
|
PhosphoSite |
PhosphoSite-Q8CBY1
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
74480
|
UniGene |
Mm.397141
|
RefSeq |
|
MGI ID |
|
MGI Symbol |
Samd4
|
OMIM |
|
CCDS |
|
HPRD |
|
IMGT |
|
EMBL |
AC131586
AC159006
AK017081
AK034323
AK134243
AK161277
AK163751
BC049740
BC145827
BC145829
CH466605
DQ278487
|
GenPept |
AAH49740
AAI45828
AAI45830
ABB83932
BAB30585
BAC28674
BAE22061
BAE36288
BAE37479
EDL20734
|
|
|