Version 5.4
Mus musculus Protein: Naa50
Summary
InnateDB Protein IDBP-533594.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Naa50
Protein Name N(alpha)-acetyltransferase 50, NatE catalytic subunit
Synonyms 2600005K24Rik; 2810441M03Rik; AW112078; Mak3; Mak3p; Nat13; Nat5; San;
Species Mus musculus
Ensembl Protein ENSMUSP00000124291
InnateDB Gene IDBG-161549 (Naa50)
Protein Structure
UniProt Annotation
Function Probable catalytic component of the NAA11-NAA15 complex which displays alpha (N-terminal) acetyltransferase activity. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:16484612}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004596 peptide alpha-N-acetyltransferase activity
GO:0005515 protein binding
GO:0008080 N-acetyltransferase activity
GO:0010485 H4 histone acetyltransferase activity
GO:0052858 peptidyl-lysine N-acetyltransferase activity
Biological Process
GO:0006474 N-terminal protein amino acid acetylation
GO:0043967 histone H4 acetylation
GO:0071962 mitotic sister chromatid cohesion, centromeric
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1919367
InterPro IPR000182 GNAT domain
IPR016181 Acyl-CoA N-acyltransferase
PFAM PF00583
PF13302
PF13508
PF13673
PF13718
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PGB6
PhosphoSite PhosphoSite-Q6PGB6
TrEMBL
UniProt Splice Variant
Entrez Gene 72117
UniGene Mm.472152
RefSeq XP_006522652
MGI ID
MGI Symbol Naa50
OMIM
CCDS
HPRD
IMGT
EMBL AK011160 AK135658 AK145345 AK156791 AK167141 AK168394 BC046283 BC055846 BC057117
GenPept AAH46283 AAH55846 AAH57117 BAB27439 BAE22602 BAE26378 BAE33858 BAE39286 BAE40319

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca