Version 5.4
Mus musculus Protein: Nbeal2
Summary
InnateDB Protein IDBP-533689.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nbeal2
Protein Name neurobeachin-like 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000121373
InnateDB Gene IDBG-202248 (Nbeal2)
Protein Structure
UniProt Annotation
Function Probably involved in thrombopoiesis. Plays a role in the development or secretion of alpha-granules, that contain several growth factors important for platelet biogenesis (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0007596 blood coagulation
GO:0030220 platelet formation
GO:0035855 megakaryocyte development
GO:0042060 wound healing
GO:0070889 platelet alpha granule organization
Cellular Component
GO:0005783 endoplasmic reticulum
Protein Structure and Domains
PDB ID MGI:2448554
InterPro IPR000409 BEACH domain
IPR001680 WD40 repeat
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR016024 Armadillo-type fold
IPR017986 WD40-repeat-containing domain
PFAM PF02138
PF00400
PRINTS
PIRSF
SMART SM01026
SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZQA0
PhosphoSite PhosphoSite-Q6ZQA0
TrEMBL
UniProt Splice Variant
Entrez Gene 235627
UniGene Mm.335481
RefSeq
MGI ID
MGI Symbol Nbeal2
OMIM
CCDS
HPRD
IMGT
EMBL AC132103 AK129158
GenPept BAC97968

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca