InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pitpnm2

Summary

InnateDB Protein

IDBP-533712.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pitpnm2

Protein Name

phosphatidylinositol transfer protein, membrane-associated 2

Synonyms

mKIAA1457; NIR3; Rdgb2; RDGBA2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000124740

InnateDB Gene

IDBG-200358 (Pitpnm2)

Protein Structure

UniProt Annotation

Function

Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro). Binds calcium ions (By similarity). {ECO:0000250}.

Subcellular Localization

Endomembrane system {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000305PubMed:10460238}. Note=May associate with the cytoskeleton.

Disease Associations

Tissue Specificity

Detected in retina and in the dentate gyrus of the cerebellum. {ECO:0000269PubMed:10460238}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005543	phospholipid binding
GO:0046872	metal ion binding

Biological Process

GO:0006810	transport
GO:0008150	biological_process

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0012505	endomembrane system
GO:0016020	membrane
GO:0043231	intracellular membrane-bounded organelle